The method development process 

All core components of the method development process for wet dispersed samples are covered by SOP Architect:

Sample preparation 

SOP Architect provides guidance on sampling best practices, dispersant selection and pre-dispersion methods such as sonication.

Dispersion stability check 

An initial stability check is performed and smart algorithms analyze the data for evidence of stability issues like agglomeration, dispersion or dissolution. If any issues are identified, support is provided to resolve them. 

Stir speed titration 

The optimal stirrer speed is selected in this automated test to achieve the most stable and representative results for your sample. The stir speed titration ensures issues like sedimentation are avoided.

*NEW* Ultrasound titration 

The required ultrasound conditions (power and duration) are selected in this automated test to ensure sample agglomerates are effectively dispersed. The ultrasound titration assists in ensuring the primary particle size of your sample is selected.

Obscuration titration 

The optimal obscuration value is selected for your sample. Enough sample is analyzed to ensure representative and accurate results without the worry of multiple scattering. 

Method repeatability check 

Multiple repeat tests are performed and the results are assessed against standard acceptance criteria (ISO 13320, USP <429>) . If the results demonstrate suitable repeatability, you are good to go! But if not, SOP Architect will provide additional support to improve your method further.

Save your SOP

Once you have completed the method development process with SOP Architect, you can save an SOP file for future use at any time. This SOP file contains all the measurement parameters needed to test your sample. Eager to start testing? Use the SOP file in the SOP Player feature. Or want to add some finishing touches? You can with SOP Editor. 

Features and benefits

SOP Architect is a tool within the Mastersizer Xplorer that can be used at any time. When it is accessed, the user can specify how much or how little of the method development process they want to focus on. The user then works through the easy-to-follow steps until they have a method that fits their requirements.

The benefits of using SOP Architect are:

• New to Mastersizer? We've got you covered.
  SOP Architect makes getting established on the Mastersizer 3000+ Ultra and Mastersizer 3000+ Pro an effortless process. 
  
  
• Any user, any sample.
  From novice to expert, SOP Architect's specialized tests and smart algorithms make it easy to develop a good method for any sample. 
  
  
• Minimize errors and maximize confidence
  Develop your methods with confidence without the fear of missing something important. SOP Architect minimizes errors and inconsistencies, helping novice users achieve high quality data and validating experts' decisions. 
  
  
• Expertise on demand.
  With a step-by-step guided workflow integrating Malvern Panalytical expertise, SOP Architect acts as a mini training session as you go. You are up and running quickly, and you'll be better prepared for your next measurements.
  
  
• Make best practices your only practices.
  By standardizing and streamlining the method development process, SOP Architect embeds best practices into your workflow and enables you to consistently achieve high standards.