Specification
Particle size and molecular size
| Measurement principle | Non-Invasive Back Scatter (NIBS) Dynamic Light Scattering
Dynamic Light Scattering (90° and 13°)
Multi-Angle Dynamic Light Scattering (MADLS)
|
|---|---|
| Measurement angle | 173°, 13°, 90° |
| Measurement range | 0.3 nm - 15 μm 2 |
| Minimum sample volume | 3 μL |
| Concentration range | Minimum sample concentration:
Blue Label: 0.2 mg/mL 15 kDa Protein
Red Label: 0.1 mg/mL 15 kDa Protein
MADLS:
0.1 mg/ml 15 kDa Protein
MADLS Particle Concentration Enabled?
Blue Label: No
Red Label: Yes
Maximum sample concentration(3):
40% w/v
|
Zeta potential
| Measurement principle | Mixed-Mode Measurement phase analysis light scattering (M3-PALS) |
|---|---|
| Size range | 3.8 nm – 100 μm |
| Minimum sample volume | 20 μL 4 |
| Concentration range | Red Label: 1 mg/mL 5 to 40% w/v 6
Blue Label: 10 mg/mL 5 to 40% w/v 6 |
| Sample conductivity range | Maximum: 260 mS/cm |
Static Light Scattering (molecular weight)
| Molecular weight range | 300 Da – 20 mDa |
|---|---|
| Measurement principle | Static Light Scattering with Debye Plot |
| Accuracy | +/- 10% |
Particle concentration
| Measurement principle | Blue Label: N/A
Red Label: MADLS - Particle Concentration (Mie) |
|---|---|
| Concentration range | Blue Label: N/A
Red Label: 1x108 to 1x1012 particles/mL |
| Calibration type | Blue Label: N/A
Red Label: Single point system calibration only |
System
| Detector | Avalanche Photodiode |
|---|---|
| Laser safety | He-Ne (633 nm)
Blue label: 4 mW Max
Red label: 10 mW Max |
| Temperature control range | 0 °C - 120 °C 7 |
| Dimensions (W, D, H) | 322 mm x 565 mm x 245 mm |
| Weight | 19 kg |
| Power | AC 100-240 V, 50-60 Hz, 4.0 A |
| Power consumption | Max 100 W, Typical 45 W |
| Ambient conditions | +10°C to +35°C, 35 to 80% RH (Non-condensing) |
| Interface | USB 2.0 or higher |
Notes
| Notes | 1 - Water as dispersant
2 - Indicative data available for particle sizes greater than 10 μm when using Extended Size Range analysis and low volume disposable sizing cell accessory.
3 - Sample dependent
4 - Using patented diffusion barrier technique
5 - Measured using 15 kDa protein
6 - Measured using bile acid
7 - Dry nitrogen cell purge required for temperatures below dewpoint
8 - Accuracy 0.1°C at 25°C, 0.2°C at 0°C, 0.5°C at 90°C
9 - Recommended upper size range for MADLS is 500nm diameter
|
|---|
